"In recent years, several methods have been developed for repairing full-thickness cartilage defects by tissue engineering using mesenchymal stem cells. Most of these use scaffolds to achieve sufficient thickness. However, considering the potential influence of scaffolds on the surrounding microenvironment, as well as immunological issues, it is desirable to develop a scaffold-free technique. In this study, we developed a novel technique, a scaffold-free autologous construct derived from bone marrow-derived mesenchymal stem cells (BM-MSCs), and successfully use this technique to regenerate cartilage and subchondral bone to repair an osteochondral defect in rabbit knees."
The importance of this article is that with this regeneration of the cartilage, patients would be able to improve significally after having surgery, there will be no more waits or bad news.
Which should be our priority now are prices and accessibility for people with a low socio-economical lifestyle.
-Abstract taken from: http://www.josr-online.com/content/9/1/98
-Image from: http://www.surgery.uwa.edu.au/research/cartilage